Noor Akhmad Setiawan Electrical Engineering and Information Technology Department Universitas Gadjah Mada Indonesia Coronary artery disease (CAD) is considered as the first killer disease in the world. [1][2]. Diagnosis of coronary artery disease is difficult, especially when there is no symptom. Much information from patients are needed in order to draw the correct diagnosis. It will be beneficial to use an advanced computer method such as artificial intelligence to build a decision support system for the diagnosis of coronary artery disease. CAD is caused by the accumulation of plaques within the walls of the coronary arteries that supply blood to